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MANCHESTER, England -- Jose Mourinho is reeling from his heaviest loss in English soccer. Pep Guardiola has matched the longest winless run of his coaching career.Things are about to get worse for one of the managers when Manchester United and Manchester City meet Wednesday in the fourth round of the English League Cup. Its the second head-to-head already this season between two coaches who had an often-tempestuous rivalry in Spain.Of the four competitions United and City are involved in this season, the League Cup is the lowest priority for both managers, but the importance of a victory at Old Trafford has intensified because of their teams current form.United has won just one of its last six Premier League games and lost 4-0 at Chelsea on Sunday, a personal embarrassment for Mourinho at his former club. City is winless in its last five matches in all competitions, matching Guardiolas career low at Barcelona in 2009.For that reason, Mourinho and Guardiola may choose not to rotate their lineups as much as they might have wanted to.Young players have to be involved in the teams good moment, and you cannot forget now the last five games we didnt win, Guardiola said Tuesday. To help the young players, you have to be involved in a good environment, with people with experience.To put three, four, five young players in at the same time is not a good idea because we have to protect them.The blue half of Manchester has had local bragging rights since Sept. 10, when City beat United 2-1 at Old Trafford in a performance that earned widespread praise for a side in the middle of a club-record winning run of 10 games. That game also underlined that United was still a work in progress under Mourinho, as subsequent results have proved.We are really, really sad, Mourinho said. But this (current period) is not for kids, this is for men.There is possibly more pressure on Mourinho on Wednesday. While Citys displays havent been that bad during its winless streak, Mourinho will want a signature victory to disprove growing concerns that he may not be able to stop the slide at United since Alex Fergusons retirement in 2013.If Mourinho plays a strong team and loses a derby for the second time in under two months, he will face even more criticism.Heres a look at some problem areas affecting the two teams, and where Mourinho and Guardiola might turn:---MANCHESTER UNITEDThere are issues for Mourinho throughout the team.Up front, Zlatan Ibrahimovic has regressed since opening the season with four goals in his first three games. He has scored just once in his last eight games in all competitions and may be left out to give Marcus Rashford a game as lone striker.Paul Pogba has stood out in only a few games since his arrival in August for a world-record fee of $116 million -- and not yet in a game of any real magnitude. Mourinho hasnt found the best position for the France international, who flourished on the left of a three-man central midfield for former team Juventus and has been tried in attacking and defensive midfield positions at United. Mourinho must decide if Pogba starts a fourth game in 10 days.Uniteds defense has now been hit by a suspected knee ligament injury to center back Eric Bailly, possibly the teams best defender this season. In a message to his club and country fans, the Ivory Coast international said on his Facebook page Tuesday: I hope to be able to play again for United and The Elephants before two months, God willing.Daley Blind and Chris Smalling may start at center back.---MANCHESTER CITYDefense is Guardiolas biggest area of concern after five winless games in which mistakes at the back have been ruthlessly punished by Celtic, Tottenham, Everton, Barcelona and Southampton.Guardiola has played three at the back in the last two league games, and may return to a four-man defense and play youngster Pablo Maffeo at right back. Another 19-year-old player, Aleix Garcia, is set to play in central midfield as Kevin De Bruyne is out with a calf injury.Sergio Aguero hasnt started two of Citys last three games, so may be one of the senior stars in the starting side. Otherwise, Kelechi Iheanacho will lead the attack. Wholesale Baseball Jerseys Online . Numbers Game examines the deal that sees Michael Del Zotto and Kevin Klein switch places. The Predators Get: D Michael Del Zotto. Cheap MLB Jerseys China . - Connor McDavid scored 53 seconds into overtime as the Erie Otters came from behind to defeat the visiting Guelph Storm 4-3 on Saturday in Ontario Hockey League action. http://www.cheapmlbjerseysusa.com/ . -- The plastic that was taped across the lockers in Oaklands clubhouse came down and the champagne that was on ice went back into the cooler. Cheap MLB Jerseys Free Shipping .S District Court against Major League Baseball, the Office of the Commissioner and his own union, the MLBPA. Discount Baseball Jerseys . Marincin has played in two NHL games so far this season with two penalty minutes. The 21-year-old has three goals, four assists and a plus-5 rating in 24 games with the American Hockey Leagues Oklahoma City Barons this season. INDIANAPOLIS -- Andrew Luck missed T.Y. Hilton on one critical play Sunday. The Colts quarterback didnt make the same mistake again.On his second chance, Luck threw a perfect strike to Hilton with 1:17 to play, and the Pro Bowl receiver spun out of a tackle and zig-zagged 63 yards down the field to give Indianapolis a 26-22 victory over San Diego.Just 35 seconds earlier, Luck tried the same play with Hilton on fourth-and-7 but an off-target throw forced Hilton to spin around for an 8-yard catch on fourth-and-7. The next time, Luck got it right.It was the same sort of play and I kind of missed him, Luck said, referring to the fourth-down throw. So I came back to him and this time I hit him in stride.Hilton took care of the rest.Its the second time on Lucks home turf that he has led the Colts (1-2) to a go-ahead score in the waning seconds. But, unlike the season opener two weeks ago, the Colts recovered two fumbles in the final 62 seconds to preserve the victory.Luck finished 24 of 37 for 331 yards with one TD and one interception to earn his 15th career come-from-behind win.No, he wasnt flawless. But when it mattered most, Luck excelled with the two big plays to Hilton.Philip Rivers got two chances to win it. The first ended when Pro Bowl safety Mike Adams recovered a fumble with 62 seconds left. The second ended when linebacker DQwell Jackson covered the bouncing ball on the Chargers last gasp desperation play.Rivers was 26 of 39 for 330 yards.You have to put teams away when you have opportunities to do it or make the plays earlier in the game, Chargers coach Mike McCoy said. We didnt do that for four quarters. We have to make those plays.STILL WAITINGChargers defensive end Joey Bosa practiced in pads for the first time this week. The No. 3 overall draft pick still has not made his NFL debut. After showing up following a prolonged contract holdout, Bosas return was set back by a hamstring injury. Now the question is how much longer will the Chargers keep him out?DIGGING OUTIndy still hasnt started 0-3 since 2011, when Peyton Manning missed the entire season with an injured nerve.dddddddddddd How big was this win? Since the current playoff format took effect in 1990, only five 0-3 teams have made the postseason and nobody has done it since the 1998 Buffalo Bills.STRANGE DAYSOn what was supposed to be the final play of the game, the Chargers had no punt returner so they could send everyone to block Pat McAfees kick. McAfee pooched it inside the Chargers 20-yard line where the Colts downed it. One problem: The refs called illegal touching, giving San Diego an untimed play. Afterward, Pagano explained the Colts werent allowed to touch it until the refs blew the ball dead.THEY SAID ITChargers: Rivers on the unsportsmanlike conduct call he drew after a 43-yard completion put San Diego at the Indy 6: Thats the most unfair penalty Ive ever gotten. Ive never gotten one like that. Ive never gotten one for really doing nothing. It maybe was the cleanest thing said on that field today and he (the official) was 30 yards away. From what I hear, it looked like nothing on the TV, but I dont know.Colts: Coach Chuck Pagano on his thoughts as Hilton broke the tackle: Probably like you guys, too much time on the clock. If youre going to score, dont score so fast.INJURY REPORTChargers: Linebacker Manti Teo came in as San Diegos leading tackler, but left in the first quarter with an Achilles tendon injury and did not return. The injury occurred when he appeared to plant his left leg while chasing Gore into the flat. McCoy said Teo will undergo tests Monday morning to confirm the initial diagnosis.Colts: The Colts played most of the game their regular starters on the right side of their offensive line. Guard Denzelle Good (back) was inactive and Reitz (back) left during the first half.---Online: AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL ' ' '